Publications from the Accelerator Consortium

Many congratulations to the Milan Centre for the first publication for the Accelerator:

Zuco V, Pasquali S, Tortoreto M, Brich S, Percio S, Dagrada G, Colombo C, Sanfilippo R, Lauricella C, Gounder M, El Bezawy R, Barisella M, Tos APD, Casali PG, Alessandro Gronchi, Stacchiotti S & Zaffaroni N. (2021). Selinexor versus doxorubicin in dedifferentiated liposarcoma PDXs: evidence of greater activity and apoptotic response dependent on p53 nuclear accumulation and survivin down-regulation. Journal of Experimental & Clinical Cancer Research, (1), doi: 10.1186/s13046-021-01886-x

Other publications:

Merry E, Thway K, Jones R, Huang P. (2021). Predictive and prognostic transcriptomic biomarkers in soft tissue sarcomas. Precision Oncology, (1), doi: 10.1038/s41698-021-00157-4

Tyler R, Wanigasooriya K, Taniere P, Almond M, Ford S, Desai A, Beggs A. (2020). A review of retroperitoneal liposarcoma genomics. Cancer treatment reviews, 86, pp. 102013. doi: 10.1016/j.ctrv.2020.102013

Accelerator Steering Committee Meeting

Our second Steering Committee Meeting was due to take place in April 2021 but due the second wave of the pandemic and the expected limitations on Board Member availability. This meeting is now postponed until 29th June 2021.

Accelerator Project Catch-up Meeting

The Project Catch-up meetings took place virtually on 12th January, 10th March and 11th May 2021.

Trial Protocol Update

• The PANTHR-S accelerator study protocol has been approved by the UK regulatory bodies and the Study Initiation Visit (SIV) is due to take place in the UK sites shortly.
• Milan and Seville Centres have submitted the protocol to their local IRB.

ResearchFish Submission

The first ResearchFish submission to Cancer Research UK was completed in March 2021. Outputs from the grants that were submitted included 3 publications and 5 grants.

Grant acknowledgement text

It is important to include the following grant acknowledgement text in manuscripts that have received funding from the Sarcoma Accelerator : ‘This work was supported by the International Accelerator Award funded by Cancer Research UK [C56167/A29363], Associazione Italiana per la Ricerca sul Cancro [AIRC - 24297] and Fundacion Científica – Asociacion Espanola Contra el Cancer [Foundation AECC - GEACC19007MA].’. The order of the funding bodies appear in the acknowledgement is flexible, as it depends on the centre that led the work in the publication.

Quarterly Informal Research Meeting

• Our first quarterly informal research meeting took place on 11th February 2021. Below is a photo of some of the participants:

• The next meeting will take place on the 17th May 2021 between 10 am to noon. Please contact Paul Huang if you wish to participate or contribute to these research meetings.